Journal of Biomedicine and Biosensors


The toxicology and pharmacology of the synthetic cathinone mephedrone

  • By Yanlin Tao, Jian Li, Xiaomeng Wang - 16 Dec 2022
  • Journal of Biomedicine and Biosensors, Volume: 2, Issue: 1, Pages: 32 - 38
  • Received: 16 February 2022; Accepted: 13 March 2022; First Online: 30 March 2022


It is common to find synthetic cathinones in recreational drugs, including mephedrone (4-methylmethcathinone). In spite of the fact that the technology has been around since 2007, its popularity has surged in recent years, both in terms of availability and use of the platform. This article's goal is to summarize published and unpublished evidence from the literature regarding the use of mephedrone, the sources that it is obtained from, and the prevalence of the use of mephedrone. Additionally, we will discuss the pharmacology of mephedrone, as well as the types of acute toxicity it may cause, as well as the reported fatalities associated with its use, as well as the potential for dependence on mephedrone.

Keywords: cathinones, mephedrone, methylmethcathinone, pharmacology