Current Research in Health Sciences

Research Article

Prognostic Risk for Prostate Cancer According to Secretor Status

  • By Alphonsus Ogbonna Ogbuabor, Miriam Obiageli Aniagolu, Emmanuel Sunday Onah - 29 Feb 2024
  • Current Research in Health Sciences, Volume: 2, Issue: 1, Pages: 9 - 15
  • https://doi.org/10.58613/crhs212
  • Received: December 2, 2023; Accepted: February 20, 2024; Published: February 29, 2024

Abstract

Background: Prostrate cancer is a leading cause of cancer mortality in Nigerian males. The Prostate Specific Antigen (PSA) is known to be a specific marker for the diagnosis of prostate cancer. Objective: To investigate the association between secretor status and prostate specific antigen levels among apparently healthy males. Materials and Methods: This was a cross sectional study of 120 serially recruited apparently healthy males aged 40 years and above. Blood group of the subjects were determined by the Tile Hemagglutination test, the secretor status by the Tube Hemagglutination test while the PSA level was determined by Sandwich Enzyme-Linked Immunosorbent Assay. Data was analyzed using the Statistical Package for Social Sciences Version 23. P < 0.05 was considered significant. Result: 41.7% of the subjects who are non-secretors have PSA values of 4ng/ml and above compared to 10.2% for secretors. Conclusion: This finding suggests that individuals who are non-secretors may be at risk for developing prostate cancer compared to secretors.